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Exploration of the Conformational Dynamics of Major Histocompatibility Complex Molecules
Major histocompatibility complex (MHC) molecules are loaded with a wide variety of self- and non-self-peptides in their binding grooves and present these to T cell receptors (TCRs) in order to activate the adaptive immune system. A large number of crystal structures of different MHC alleles with dif...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446982/ https://www.ncbi.nlm.nih.gov/pubmed/28611781 http://dx.doi.org/10.3389/fimmu.2017.00632 |