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Analysis of Complement C3 Gene Reveals Susceptibility to Severe Preeclampsia

Preeclampsia (PE) is a common vascular disease of pregnancy with genetic predisposition. Dysregulation of the complement system has been implicated, but molecular mechanisms are incompletely understood. In this study, we determined the potential linkage of severe PE to the most central complement ge...

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Detalles Bibliográficos
Autores principales: Lokki, A. Inkeri, Kaartokallio, Tea, Holmberg, Ville, Onkamo, Päivi, Koskinen, Lotta L. E., Saavalainen, Päivi, Heinonen, Seppo, Kajantie, Eero, Kere, Juha, Kivinen, Katja, Pouta, Anneli, Villa, Pia M., Hiltunen, Leena, Laivuori, Hannele, Meri, Seppo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446983/
https://www.ncbi.nlm.nih.gov/pubmed/28611769
http://dx.doi.org/10.3389/fimmu.2017.00589