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The Distribution of Charged Amino Acid Residues and the Ca(2+) Permeability of Nicotinic Acetylcholine Receptors: A Predictive Model
Nicotinic acetylcholine receptors (nAChRs) are cation-selective ligand-gated ion channels exhibiting variable Ca(2+) permeability depending on their subunit composition. The Ca(2+) permeability is a crucial functional parameter to understand the physiological role of nAChRs, in particular considerin...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447003/ https://www.ncbi.nlm.nih.gov/pubmed/28611586 http://dx.doi.org/10.3389/fnmol.2017.00155 |