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4R-Cembranoid Improves Outcomes after 6-Hydroxydopamine Challenge in Both In vitro and In vivo Models of Parkinson's Disease

(1S, 2E, 4R, 6R,-7E, 11E)-2, 7, 11-cembratriene-4, 6-diol (4R) is one of the cembranoids found in tobacco leaves. Previous studies have found that 4R protected acute rat hippocampal slices against neurotoxicity induced by N-methyl-D-aspartate (NMDA) and against the toxic organophosphorus compounds p...

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Detalles Bibliográficos
Autores principales: Hu, Jing, Ferchmin, P. A., Hemmerle, Ann M., Seroogy, Kim B., Eterovic, Vesna A., Hao, Jiukuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447022/
https://www.ncbi.nlm.nih.gov/pubmed/28611572
http://dx.doi.org/10.3389/fnins.2017.00272