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Glial and Neuronal Glutamate Transporters Differ in the Na(+) Requirements for Activation of the Substrate-Independent Anion Conductance
Excitatory amino acid transporters (EAATs) are secondary active transporters of L-glutamate and L- or D-aspartate. These carriers also mediate a thermodynamically uncoupled anion conductance that is gated by Na(+) and substrate binding. The activation of the anion channel by binding of Na(+) alone,...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447070/ https://www.ncbi.nlm.nih.gov/pubmed/28611584 http://dx.doi.org/10.3389/fnmol.2017.00150 |