Glial and Neuronal Glutamate Transporters Differ in the Na(+) Requirements for Activation of the Substrate-Independent Anion Conductance

Excitatory amino acid transporters (EAATs) are secondary active transporters of L-glutamate and L- or D-aspartate. These carriers also mediate a thermodynamically uncoupled anion conductance that is gated by Na(+) and substrate binding. The activation of the anion channel by binding of Na(+) alone,...

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Detalles Bibliográficos
Autores principales: Divito, Christopher B., Borowski, Jenna E., Glasgow, Nathan G., Gonzalez-Suarez, Aneysis D., Torres-Salazar, Delany, Johnson, Jon W., Amara, Susan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447070/
https://www.ncbi.nlm.nih.gov/pubmed/28611584
http://dx.doi.org/10.3389/fnmol.2017.00150

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