Icariin, a Novel Blocker of Sodium and Calcium Channels, Eliminates Early and Delayed Afterdepolarizations, As Well As Triggered Activity, in Rabbit Cardiomyocytes

Icariin, a flavonoid monomer from Herba Epimedii, has confirmed pharmacological and biological effects. However, its effects on arrhythmias and cardiac electrophysiology remain unclear. Here we investigate the effects of icariin on ion currents and action potentials (APs) in the rabbit myocardium. F...

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Detalles Bibliográficos
Autores principales: Jiang, Wanzhen, Zeng, Mengliu, Cao, Zhenzhen, Liu, Zhipei, Hao, Jie, Zhang, Peipei, Tian, Youjia, Zhang, Peihua, Ma, Jihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447092/
https://www.ncbi.nlm.nih.gov/pubmed/28611679
http://dx.doi.org/10.3389/fphys.2017.00342

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447092/
https://www.ncbi.nlm.nih.gov/pubmed/28611679
http://dx.doi.org/10.3389/fphys.2017.00342

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