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Icariin, a Novel Blocker of Sodium and Calcium Channels, Eliminates Early and Delayed Afterdepolarizations, As Well As Triggered Activity, in Rabbit Cardiomyocytes
Icariin, a flavonoid monomer from Herba Epimedii, has confirmed pharmacological and biological effects. However, its effects on arrhythmias and cardiac electrophysiology remain unclear. Here we investigate the effects of icariin on ion currents and action potentials (APs) in the rabbit myocardium. F...
Autores principales: | Jiang, Wanzhen, Zeng, Mengliu, Cao, Zhenzhen, Liu, Zhipei, Hao, Jie, Zhang, Peipei, Tian, Youjia, Zhang, Peihua, Ma, Jihua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447092/ https://www.ncbi.nlm.nih.gov/pubmed/28611679 http://dx.doi.org/10.3389/fphys.2017.00342 |
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