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Discovery and Development of Calcium Channel Blockers
In the mid 1960s, experimental work on molecules under screening as coronary dilators allowed the discovery of the mechanism of calcium entry blockade by drugs later named calcium channel blockers. This paper summarizes scientific research on these small molecules interacting directly with L-type vo...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447095/ https://www.ncbi.nlm.nih.gov/pubmed/28611661 http://dx.doi.org/10.3389/fphar.2017.00286 |