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Discovery and Development of Calcium Channel Blockers

In the mid 1960s, experimental work on molecules under screening as coronary dilators allowed the discovery of the mechanism of calcium entry blockade by drugs later named calcium channel blockers. This paper summarizes scientific research on these small molecules interacting directly with L-type vo...

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Detalles Bibliográficos
Autor principal: Godfraind, Théophile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447095/
https://www.ncbi.nlm.nih.gov/pubmed/28611661
http://dx.doi.org/10.3389/fphar.2017.00286