CHRR: coordinate hit-and-run with rounding for uniform sampling of constraint-based models

SUMMARY: In constraint-based metabolic modelling, physical and biochemical constraints define a polyhedral convex set of feasible flux vectors. Uniform sampling of this set provides an unbiased characterization of the metabolic capabilities of a biochemical network. However, reliable uniform samplin...

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Detalles Bibliográficos
Autores principales: Haraldsdóttir, Hulda S, Cousins, Ben, Thiele, Ines, Fleming, Ronan M.T, Vempala, Santosh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Applications Notes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447232/
https://www.ncbi.nlm.nih.gov/pubmed/28158334
http://dx.doi.org/10.1093/bioinformatics/btx052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447232/
https://www.ncbi.nlm.nih.gov/pubmed/28158334
http://dx.doi.org/10.1093/bioinformatics/btx052

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