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Delayed Mesoderm and Erythroid Differentiation of Murine Embryonic Stem Cells in the Absence of the Transcriptional Regulator FUBP1

The transcriptional regulator far upstream binding protein 1 (FUBP1) is essential for fetal and adult hematopoietic stem cell (HSC) self-renewal, and the constitutive absence of FUBP1 activity during early development leads to embryonic lethality in homozygous mutant mice. To investigate the role of...

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Detalles Bibliográficos
Autores principales: Wesely, Josephine, Steiner, Marlene, Schnütgen, Frank, Kaulich, Manuel, Rieger, Michael A., Zörnig, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447289/
https://www.ncbi.nlm.nih.gov/pubmed/28588622
http://dx.doi.org/10.1155/2017/5762301