Cargando…

HMGB1-RAGE pathway drives peroxynitrite signaling-induced IBD-like inflammation in murine nonalcoholic fatty liver disease

Recent clinical studies found a strong association of colonic inflammation and Inflammatory bowel disease (IBD)-like phenotype with NonAlcoholic Fatty liver Disease (NAFLD) yet the mechanisms remain unknown. The present study identifies high mobility group box 1 (HMGB1) as a key mediator of intestin...

Descripción completa

Detalles Bibliográficos
Autores principales: Chandrashekaran, Varun, Seth, Ratanesh K., Dattaroy, Diptadip, Alhasson, Firas, Ziolenka, Jacek, Carson, James, Berger, Franklin G., Kalyanaraman, Balaraman, Diehl, Anna Mae, Chatterjee, Saurabh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447385/
https://www.ncbi.nlm.nih.gov/pubmed/28551086
http://dx.doi.org/10.1016/j.redox.2017.05.005