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HMGB1-RAGE pathway drives peroxynitrite signaling-induced IBD-like inflammation in murine nonalcoholic fatty liver disease
Recent clinical studies found a strong association of colonic inflammation and Inflammatory bowel disease (IBD)-like phenotype with NonAlcoholic Fatty liver Disease (NAFLD) yet the mechanisms remain unknown. The present study identifies high mobility group box 1 (HMGB1) as a key mediator of intestin...
Autores principales: | Chandrashekaran, Varun, Seth, Ratanesh K., Dattaroy, Diptadip, Alhasson, Firas, Ziolenka, Jacek, Carson, James, Berger, Franklin G., Kalyanaraman, Balaraman, Diehl, Anna Mae, Chatterjee, Saurabh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447385/ https://www.ncbi.nlm.nih.gov/pubmed/28551086 http://dx.doi.org/10.1016/j.redox.2017.05.005 |
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