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Dexmedetomidine attenuates neuropathic pain in chronic constriction injury by suppressing NR2B, NF-κB, and iNOS activation

The effective treatment of patients suffering from neuropathic pain remains challenging. Dexmedetomidine (DEX) possesses anti-inflammatory activity. However, the role of DEX in neuropathic pain is still unclear. The aim of the present study was to examine DEX an α2-adrenoceptor agonist could improve...

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Detalles Bibliográficos
Autores principales: Liang, Feng, Liu, Miao, Fu, Xin, Zhou, Xueying, Chen, Peng, Han, Fanglei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447440/
https://www.ncbi.nlm.nih.gov/pubmed/28579906
http://dx.doi.org/10.1016/j.jsps.2017.04.039