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Pharmacokinetics of a liposomal formulation of doxorubicin in rats

Background: Measuring free drug concentration following systemic administration of a liposomal drug is a crucial aspect of the assessment of its in vivo behavior. Therefore we require an efficient method to separate free drug in the plasma from encapsulated drug. Objectives: To study the pharmacokin...

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Detalles Bibliográficos
Autores principales: Liu, Zongyu, Bi, Ye, Sun, Yating, Hao, Fei, Lu, Jiahui, Meng, Qingfan, Lee, Robert J., Tian, Yaping, Xie, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447445/
https://www.ncbi.nlm.nih.gov/pubmed/28579888
http://dx.doi.org/10.1016/j.jsps.2017.04.019