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Diametric Role of the Latency-Associated Protein Acr1 of Mycobacterium tuberculosis in Modulating the Functionality of Pre- and Post-maturational Stages of Dendritic Cells

It is instrumental for the Mycobacterium tuberculosis (Mtb) to persist within its host in dormancy. Mtb represses most of its metabolic machinery during latency, but upregulates the expression of latency-associated protein alpha-crystallin protein (Acr1). Therefore, it is imperative to understand ho...

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Detalles Bibliográficos
Autores principales: Amir, Mohammed, Aqdas, Mohammad, Nadeem, Sajid, Siddiqui, Kaneez F., Khan, Nargis, Sheikh, Javaid A., Agrewala, Javed N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447689/
https://www.ncbi.nlm.nih.gov/pubmed/28611779
http://dx.doi.org/10.3389/fimmu.2017.00624