Cargando…

mTORC1 Is a Local, Postsynaptic Voltage Sensor Regulated by Positive and Negative Feedback Pathways

The mammalian/mechanistic target of rapamycin complex 1 (mTORC1) serves as a regulator of mRNA translation. Recent studies suggest that mTORC1 may also serve as a local, voltage sensor in the postsynaptic region of neurons. Considering biochemical, bioinformatics and imaging data, we hypothesize tha...

Descripción completa

Detalles Bibliográficos
Autores principales: Niere, Farr, Raab-Graham, Kimberly F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447718/
https://www.ncbi.nlm.nih.gov/pubmed/28611595
http://dx.doi.org/10.3389/fncel.2017.00152