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Selective Tissue Distribution Mediates Tissue-Dependent PPARγ Activation and Insulin Sensitization by INT131, a Selective PPARγ Modulator

The mechanisms underlying the enhancement of insulin sensitivity by selective peroxisome proliferator-activated receptor γ modulators (sPPARγMs) are still not completely known. Here, the representative sPPARγM, INT131, was used as a probe to investigate the insulin-sensitizing mechanisms of sPPARγM...

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Detalles Bibliográficos
Autores principales: Xie, Xinni, Chen, Wei, Zhang, Ning, Yuan, Mei, Xu, Cheng, Zheng, Zhibing, Li, Hua, Wang, Lili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447729/
https://www.ncbi.nlm.nih.gov/pubmed/28611668
http://dx.doi.org/10.3389/fphar.2017.00317