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Protective Role for LPA(3) in Cardiac Hypertrophy Induced by Myocardial Infarction but Not by Isoproterenol

Background: We previously reported that lysophosphatidic acid (LPA) promoted cardiomyocyte hypertrophy in vitro via one of its G protein-coupled receptor subtypes, LPA(3). In this study, we examined the role of LPA(3) in cardiac hypertrophy induced by isoproterenol (ISO) and myocardial infarction. M...

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Detalles Bibliográficos
Autores principales: Cai, Lin, Fan, Guangpu, Wang, Fang, Liu, Si, Li, Tiewei, Cong, Xiangfeng, Chun, Jerold, Chen, Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447740/
https://www.ncbi.nlm.nih.gov/pubmed/28611684
http://dx.doi.org/10.3389/fphys.2017.00356