Identification of Epigallocatechin-3- Gallate as an Inhibitor of Phosphoglycerate Mutase 1

Targeting metabolic enzymes is believed to provide new therapeutic opportunities for cancer therapy. Phosphoglycerate mutase 1 (PGAM1) is a glycolytic enzyme that importantly coordinates glycolysis, pentose phosphate pathway (PPP) flux and serine biosynthesis in cancer cells and hence gains increasi...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Xiaoguang, Tang, Shuai, Wang, Qian-Qian, Leung, Elaine L.-H., Jin, Hongyue, Huang, Yongzhuo, Liu, Jia, Geng, Meiyu, Huang, Min, Yuan, Shengtao, Yao, Xiao-Jun, Ding, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447756/
https://www.ncbi.nlm.nih.gov/pubmed/28611670
http://dx.doi.org/10.3389/fphar.2017.00325

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447756/
https://www.ncbi.nlm.nih.gov/pubmed/28611670
http://dx.doi.org/10.3389/fphar.2017.00325

Ejemplares similares