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Identification of Epigallocatechin-3- Gallate as an Inhibitor of Phosphoglycerate Mutase 1

Targeting metabolic enzymes is believed to provide new therapeutic opportunities for cancer therapy. Phosphoglycerate mutase 1 (PGAM1) is a glycolytic enzyme that importantly coordinates glycolysis, pentose phosphate pathway (PPP) flux and serine biosynthesis in cancer cells and hence gains increasi...

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Detalles Bibliográficos
Autores principales:	Li, Xiaoguang, Tang, Shuai, Wang, Qian-Qian, Leung, Elaine L.-H., Jin, Hongyue, Huang, Yongzhuo, Liu, Jia, Geng, Meiyu, Huang, Min, Yuan, Shengtao, Yao, Xiao-Jun, Ding, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447756/ https://www.ncbi.nlm.nih.gov/pubmed/28611670 http://dx.doi.org/10.3389/fphar.2017.00325

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