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Targeting Hypoxia Inducible Factors-1α As a Novel Therapy in Fibrosis
Fibrosis, characterized by increased extracellular matrix (ECM) deposition, and widespread vasculopathy, has the prominent trait of chronic hypoxia. Hypoxia inducible factors-1α (HIF-1α), a key transcriptional factor in response to this chronic hypoxia, is involved in fibrotic disease, such as Syste...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447768/ https://www.ncbi.nlm.nih.gov/pubmed/28611671 http://dx.doi.org/10.3389/fphar.2017.00326 |