MTH1 as a Chemotherapeutic Target: The Elephant in the Room

Many tumors sustain elevated levels of reactive oxygen species (ROS), which drive oncogenic signaling. However, ROS can also trigger anti-tumor responses, such as cell death or senescence, through induction of oxidative stress and concomitant DNA damage. To circumvent the adverse consequences of ele...

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Detalles Bibliográficos
Autores principales: Samaranayake, Govindi J., Huynh, Mai, Rai, Priyamvada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447957/
https://www.ncbi.nlm.nih.gov/pubmed/28481306
http://dx.doi.org/10.3390/cancers9050047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447957/
https://www.ncbi.nlm.nih.gov/pubmed/28481306
http://dx.doi.org/10.3390/cancers9050047

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