MB0 and MBI Are Independent and Distinct Transactivation Domains in MYC that Are Essential for Transformation

MYC is a transcription factor that is essential for cellular proliferation and development. Deregulation or overexpression of MYC occurs in a variety of human cancers. Ectopic expression of MYC causes hyperproliferation and transformation of cells in culture and tumorigenesis in several transgenic m...

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Detalles Bibliográficos
Autores principales: Zhang, Qin, West-Osterfield, Kimberly, Spears, Erick, Li, Zhaoliang, Panaccione, Alexander, Hann, Stephen R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448008/
https://www.ncbi.nlm.nih.gov/pubmed/28481271
http://dx.doi.org/10.3390/genes8050134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448008/
https://www.ncbi.nlm.nih.gov/pubmed/28481271
http://dx.doi.org/10.3390/genes8050134

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