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The Role of the N-Terminal Domains of Bacterial Initiator DnaA in the Assembly and Regulation of the Bacterial Replication Initiation Complex

The primary role of the bacterial protein DnaA is to initiate chromosomal replication. The DnaA protein binds to DNA at the origin of chromosomal replication (oriC) and assembles into a filament that unwinds double-stranded DNA. Through interaction with various other proteins, DnaA also controls the...

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Detalles Bibliográficos
Autores principales: Zawilak-Pawlik, Anna, Nowaczyk, Małgorzata, Zakrzewska-Czerwińska, Jolanta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448010/
https://www.ncbi.nlm.nih.gov/pubmed/28489024
http://dx.doi.org/10.3390/genes8050136