Mutational and Kinetic Analysis of Lesion Recognition by Escherichia coli Endonuclease VIII

Escherichia coli endonuclease VIII (Endo VIII) is a DNA glycosylase with substrate specificity for a wide range of oxidatively damaged pyrimidine bases. Endo VIII catalyzes hydrolysis of the N-glycosidic bond and β, δ-elimination of 3′- and 5′-phosphate groups of an apurinic/apyrimidinic site. Singl...

Descripción completa

Detalles Bibliográficos
Autores principales: Kladova, Olga A., Kuznetsova, Alexandra A., Fedorova, Olga S., Kuznetsov, Nikita A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448014/
https://www.ncbi.nlm.nih.gov/pubmed/28505099
http://dx.doi.org/10.3390/genes8050140

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448014/
https://www.ncbi.nlm.nih.gov/pubmed/28505099
http://dx.doi.org/10.3390/genes8050140

Ejemplares similares