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Mutational and Kinetic Analysis of Lesion Recognition by Escherichia coli Endonuclease VIII

Escherichia coli endonuclease VIII (Endo VIII) is a DNA glycosylase with substrate specificity for a wide range of oxidatively damaged pyrimidine bases. Endo VIII catalyzes hydrolysis of the N-glycosidic bond and β, δ-elimination of 3′- and 5′-phosphate groups of an apurinic/apyrimidinic site. Singl...

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Detalles Bibliográficos
Autores principales:	Kladova, Olga A., Kuznetsova, Alexandra A., Fedorova, Olga S., Kuznetsov, Nikita A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448014/ https://www.ncbi.nlm.nih.gov/pubmed/28505099 http://dx.doi.org/10.3390/genes8050140

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