Epigenetic Regulation of Telomere Maintenance for Therapeutic Interventions in Gliomas

High-grade astrocytoma of WHO grade 4 termed glioblastoma multiforme (GBM) is a common human brain tumor with poor patient outcome. Astrocytoma demonstrates two known telomere maintenance mechanisms (TMMs) based on telomerase activity (TA) and on alternative lengthening of telomeres (ALT). ALT is as...

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Detalles Bibliográficos
Autores principales: Naderlinger, Elisabeth, Holzmann, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448019/
https://www.ncbi.nlm.nih.gov/pubmed/28513547
http://dx.doi.org/10.3390/genes8050145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448019/
https://www.ncbi.nlm.nih.gov/pubmed/28513547
http://dx.doi.org/10.3390/genes8050145

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