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Epigenetic Regulation of Telomere Maintenance for Therapeutic Interventions in Gliomas
High-grade astrocytoma of WHO grade 4 termed glioblastoma multiforme (GBM) is a common human brain tumor with poor patient outcome. Astrocytoma demonstrates two known telomere maintenance mechanisms (TMMs) based on telomerase activity (TA) and on alternative lengthening of telomeres (ALT). ALT is as...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448019/ https://www.ncbi.nlm.nih.gov/pubmed/28513547 http://dx.doi.org/10.3390/genes8050145 |