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Defining the RNaseH2 enzyme-initiated ribonucleotide excision repair pathway in Archaea

Incorporation of ribonucleotides during DNA replication has severe consequences for genome stability. Although eukaryotes possess a number of redundancies for initiating and completing repair of misincorporated ribonucleotides, archaea such as Thermococcus rely only upon RNaseH2 to initiate the path...

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Detalles Bibliográficos
Autores principales: Heider, Margaret R., Burkhart, Brett W., Santangelo, Thomas J., Gardner, Andrew F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448109/
https://www.ncbi.nlm.nih.gov/pubmed/28373277
http://dx.doi.org/10.1074/jbc.M117.783472