High‐throughput CRISPRi phenotyping identifies new essential genes in Streptococcus pneumoniae

Genome‐wide screens have discovered a large set of essential genes in the opportunistic human pathogen Streptococcus pneumoniae. However, the functions of many essential genes are still unknown, hampering vaccine development and drug discovery. Based on results from transposon sequencing (Tn‐seq), w...

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Detalles Bibliográficos
Autores principales: Liu, Xue, Gallay, Clement, Kjos, Morten, Domenech, Arnau, Slager, Jelle, van Kessel, Sebastiaan P, Knoops, Kèvin, Sorg, Robin A, Zhang, Jing‐Ren, Veening, Jan‐Willem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448163/
https://www.ncbi.nlm.nih.gov/pubmed/28490437
http://dx.doi.org/10.15252/msb.20167449

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448163/
https://www.ncbi.nlm.nih.gov/pubmed/28490437
http://dx.doi.org/10.15252/msb.20167449

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