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An immediate–late gene expression module decodes ERK signal duration

The RAF‐MEK‐ERK signalling pathway controls fundamental, often opposing cellular processes such as proliferation and apoptosis. Signal duration has been identified to play a decisive role in these cell fate decisions. However, it remains unclear how the different early and late responding gene expre...

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Detalles Bibliográficos
Autores principales: Uhlitz, Florian, Sieber, Anja, Wyler, Emanuel, Fritsche‐Guenther, Raphaela, Meisig, Johannes, Landthaler, Markus, Klinger, Bertram, Blüthgen, Nils
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448165/
https://www.ncbi.nlm.nih.gov/pubmed/28468958
http://dx.doi.org/10.15252/msb.20177554