Nitrosative stress induces DNA strand breaks but not caspase mediated apoptosis in a lung cancer cell line

BACKGROUND: Key steps crucial to the process of tumor progression are genomic instability and escape from apoptosis. Nitric oxide and its interrelated reactive intermediates (collectively denoted as NO(X)) have been implicated in DNA damage and mutational events leading to cancer development, while...

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Detalles Bibliográficos
Autores principales: Bentz, Brandon G, Hammer, Neal D, Radosevich, James A, Haines, G Kenneth
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC544845/
https://www.ncbi.nlm.nih.gov/pubmed/15617570
http://dx.doi.org/10.1186/1477-3163-3-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC544845/
https://www.ncbi.nlm.nih.gov/pubmed/15617570
http://dx.doi.org/10.1186/1477-3163-3-16

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