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Nitrosative stress induces DNA strand breaks but not caspase mediated apoptosis in a lung cancer cell line
BACKGROUND: Key steps crucial to the process of tumor progression are genomic instability and escape from apoptosis. Nitric oxide and its interrelated reactive intermediates (collectively denoted as NO(X)) have been implicated in DNA damage and mutational events leading to cancer development, while...
Autores principales: | Bentz, Brandon G, Hammer, Neal D, Radosevich, James A, Haines, G Kenneth |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC544845/ https://www.ncbi.nlm.nih.gov/pubmed/15617570 http://dx.doi.org/10.1186/1477-3163-3-16 |
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