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Estrogen receptor-dependent attenuation of hypoxia-induced changes in the lung genome of pulmonary hypertension rats

17β-estradiol (E2) exerts complex and context-dependent effects in pulmonary hypertension. In hypoxia-induced pulmonary hypertension (HPH), E2 attenuates lung vascular remodeling through estrogen receptor (ER)-dependent effects; however, ER target genes in the hypoxic lung remain unknown. In order t...

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Detalles Bibliográficos
Autores principales:	Frump, Andrea L., Albrecht, Marjorie E., McClintick, Jeanette N., Lahm, Tim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2017
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448529/ https://www.ncbi.nlm.nih.gov/pubmed/28680582 http://dx.doi.org/10.1177/2045893217702055

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