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PPARγ attenuates hypoxia-induced hypertrophic transcriptional pathways in the heart

Chronic hypoxia-induced pulmonary hypertension (PH) is characterized by increased pressure and resistance in the pulmonary vasculature and hypertrophy of the right ventricle (RV). The transcription factors, nuclear factor activated T-cells (NFAT), and nuclear factor kappa-light-chain-enhancer of act...

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Detalles Bibliográficos
Autores principales: Chaudhry, Abubakr, Carthan, Kristal A., Kang, Bum-Yong, Calvert, John, Sutliff, Roy L., Michael Hart, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448534/
https://www.ncbi.nlm.nih.gov/pubmed/28680569
http://dx.doi.org/10.1086/689749