Dysfunctional BMPR2 signaling drives an abnormal endothelial requirement for glutamine in pulmonary arterial hypertension

Pulmonary arterial hypertension (PAH) is increasingly recognized as a systemic disease driven by alteration in the normal functioning of multiple metabolic pathways affecting all of the major carbon substrates, including amino acids. We found that human pulmonary hypertension patients (WHO Group I,...

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Detalles Bibliográficos
Autores principales: Egnatchik, Robert A., Brittain, Evan L., Shah, Amy T., Fares, Wassim H., Ford, H. James, Monahan, Ken, Kang, Christie J., Kocurek, Emily G., Zhu, Shijun, Luong, Thong, Nguyen, Thuy T., Hysinger, Erik, Austin, Eric D., Skala, Melissa C., Young, Jamey D., Roberts, L. Jackson, Hemnes, Anna R., West, James, Fessel, Joshua P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448547/
https://www.ncbi.nlm.nih.gov/pubmed/28680578
http://dx.doi.org/10.1086/690236

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448547/
https://www.ncbi.nlm.nih.gov/pubmed/28680578
http://dx.doi.org/10.1086/690236

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