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Discovery of Mieap‐regulated mitochondrial quality control as a new function of tumor suppressor p53

The tumor suppressor p53 gene is frequently mutated in human cancers, and the p53 protein suppresses cancer. However, the mechanism behind the p53‐mediated tumor suppression is still unclear. Recently, the mitochondria‐eating protein (Mieap) was identified as a p53‐inducible protein. Mieap induces t...

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Detalles Bibliográficos
Autores principales: Nakamura, Yasuyuki, Arakawa, Hirofumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448595/
https://www.ncbi.nlm.nih.gov/pubmed/28222492
http://dx.doi.org/10.1111/cas.13208