YPC‐21661 and YPC‐22026, novel small molecules, inhibit ZNF143 activity in vitro and in vivo

Zinc‐finger protein 143 (ZNF143) is a transcription factor that is involved in anticancer drug resistance and cancer cell survival. In the present study, we identified a novel small molecule N‐(5‐bromo‐2‐methoxyphenyl)‐3‐(pyridine‐3‐yl) propiolamide (YPC‐21661) that inhibited ZNF143 promoter activit...

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Detalles Bibliográficos
Autores principales: Haibara, Hirotaka, Yamazaki, Ryuta, Nishiyama, Yukiko, Ono, Masahiro, Kobayashi, Tsuneyuki, Hokkyo‐Itagaki, Atsuko, Nishisaka, Fukiko, Nishiyama, Hiroyuki, Kurita, Akinobu, Matsuzaki, Takeshi, Izumi, Hiroto, Kohno, Kimitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448606/
https://www.ncbi.nlm.nih.gov/pubmed/28192620
http://dx.doi.org/10.1111/cas.13199

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448606/
https://www.ncbi.nlm.nih.gov/pubmed/28192620
http://dx.doi.org/10.1111/cas.13199

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