SNIPER(TACC3) induces cytoplasmic vacuolization and sensitizes cancer cells to Bortezomib

We previously developed a hybrid small molecule SNIPER (Specific and Nongenetic IAP‐dependent Protein ERaser) against transforming acidic coiled‐coil‐3 (TACC3), SNIPER(TACC3), that induces proteasomal degradation of TACC3 protein. In this study, we found that SNIPER(TACC3) induces cytoplasmic vacuol...

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Detalles Bibliográficos
Autores principales: Ohoka, Nobumichi, Nagai, Katsunori, Shibata, Norihito, Hattori, Takayuki, Nara, Hiroshi, Cho, Nobuo, Naito, Mikihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448626/
https://www.ncbi.nlm.nih.gov/pubmed/28192613
http://dx.doi.org/10.1111/cas.13198

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448626/
https://www.ncbi.nlm.nih.gov/pubmed/28192613
http://dx.doi.org/10.1111/cas.13198

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