Novel small molecule inhibiting CDCP1‐PKCδ pathway reduces tumor metastasis and proliferation

CUB domain‐containing protein‐1 (CDCP1) is a trans‐membrane protein predominantly expressed in various cancer cells and involved in tumor progression. CDCP1 is phosphorylated at tyrosine residues in the intracellular domain by Src family kinases and recruits PKCδ to the plasma membrane through tyros...

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Detalles Bibliográficos
Autores principales: Nakashima, Katsuhiko, Uekita, Takamasa, Yano, Shigenobu, Kikuchi, Jun‐ichi, Nakanishi, Ruri, Sakamoto, Nozomi, Fukumoto, Keisuke, Nomoto, Akihiro, Kawamoto, Keisuke, Shibahara, Takashi, Yamaguchi, Hideki, Sakai, Ryuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448658/
https://www.ncbi.nlm.nih.gov/pubmed/28256037
http://dx.doi.org/10.1111/cas.13218

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448658/
https://www.ncbi.nlm.nih.gov/pubmed/28256037
http://dx.doi.org/10.1111/cas.13218

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