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Enhanced expression of the M2 isoform of pyruvate kinase is involved in gastric cancer development by regulating cancer‐specific metabolism

Recent studies have indicated that increased expression of the M2 isoform of pyruvate kinase (PKM2) is involved in glycolysis and tumor development. However, little is known about the role of PKM2 in gastric cancer (GC). Therefore, we examined the expression and function of PKM2 in human GC. We eval...

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Detalles Bibliográficos
Autores principales: Shiroki, Takeharu, Yokoyama, Misa, Tanuma, Nobuhiro, Maejima, Ryuhei, Tamai, Keiichi, Yamaguchi, Kazunori, Oikawa, Tomoyuki, Noguchi, Tetsuya, Miura, Koh, Fujiya, Tsuneaki, Shima, Hiroshi, Sato, Ikuro, Murata‐Kamiya, Naoko, Hatakeyama, Masanori, Iijima, Katsunori, Shimosegawa, Tooru, Satoh, Kennichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448664/
https://www.ncbi.nlm.nih.gov/pubmed/28235245
http://dx.doi.org/10.1111/cas.13211