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Basis of catalytic assembly of the mitotic checkpoint complex

Accurate genome inheritance by daughter cells requires that sister chromatids in the mother attach to microtubules emanating from opposite poles of the mitotic spindle (bi-orientation). A surveillance mechanism named the spindle assembly checkpoint (SAC) monitors the microtubule attachment process,...

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Detalles Bibliográficos
Autores principales: Faesen, Alex C., Thanasoula, Maria, Maffini, Stefano, Breit, Claudia, Müller, Franziska, van Gerwen, Suzan, Bange, Tanja, Musacchio, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448665/
https://www.ncbi.nlm.nih.gov/pubmed/28102834
http://dx.doi.org/10.1038/nature21384