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Reverse epitope mapping of the E2 glycoprotein in antibody associated hepatitis C virus

The humoral immune system responds to chronic hepatitis C virus (HCV) infection by producing neutralising antibodies (nAb). In this study we generated three HCV pseudoparticles in which E1E2 glycoprotein sequence was targeted by the host humoral immune system. We used patient derived virus free Fabs...

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Detalles Bibliográficos
Autores principales: Naik, Amruta S., Owsianka, Ania, Palmer, Brendan A., O’Halloran, Ciaran J., Walsh, Nicole, Crosbie, Orla, Kenny-Walsh, Elizabeth, Patel, Arvind H., Fanning, Liam J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448734/
https://www.ncbi.nlm.nih.gov/pubmed/28558001
http://dx.doi.org/10.1371/journal.pone.0175349