Cargando…

Overexpression of the human DEK oncogene reprograms cellular metabolism and promotes glycolysis

The DEK oncogene is overexpressed in many human malignancies including at early tumor stages. Our reported in vitro and in vivo models of squamous cell carcinoma have demonstrated that DEK contributes functionally to cellular and tumor survival and to proliferation. However, the underlying molecular...

Descripción completa

Detalles Bibliográficos
Autores principales: Matrka, Marie C., Watanabe, Miki, Muraleedharan, Ranjithmenon, Lambert, Paul F., Lane, Andrew N., Romick-Rosendale, Lindsey E., Wells, Susanne I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448751/
https://www.ncbi.nlm.nih.gov/pubmed/28558019
http://dx.doi.org/10.1371/journal.pone.0177952