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The pathogenic role of interleukin-22 and its receptor during UVB-induced skin inflammation

Recent studies show that IL-22, a cytokine produced by activated CD4(+) T cells and NK cells, plays a pathogenic role in acute and chronic skin diseases. While IL-22 is produced by immune cells, the expression of IL-22Rα, the functional subunit of IL-22R, is mostly restricted to non-hematopoietic ce...

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Detalles Bibliográficos
Autores principales: Kim, Yejin, Lee, Junmyung, Kim, Jihoon, Choi, Chong Won, Hwang, Young-Il, Kang, Jae Seung, Lee, Wang Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448782/
https://www.ncbi.nlm.nih.gov/pubmed/28558005
http://dx.doi.org/10.1371/journal.pone.0178567