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Gene duplication and co-evolution of G1/S transcription factor specificity in fungi are essential for optimizing cell fitness

Transcriptional regulatory networks play a central role in optimizing cell survival. How DNA binding domains and cis-regulatory DNA binding sequences have co-evolved to allow the expansion of transcriptional networks and how this contributes to cellular fitness remains unclear. Here we experimentall...

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Detalles Bibliográficos
Autores principales: Hendler, Adi, Medina, Edgar M., Kishkevich, Anastasiya, Abu-Qarn, Mehtap, Klier, Steffi, Buchler, Nicolas E., de Bruin, Robertus A. M., Aharoni, Amir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448814/
https://www.ncbi.nlm.nih.gov/pubmed/28505153
http://dx.doi.org/10.1371/journal.pgen.1006778