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An independent component analysis confounding factor correction framework for identifying broad impact expression quantitative trait loci
Genome-wide expression Quantitative Trait Loci (eQTL) studies in humans have provided numerous insights into the genetics of both gene expression and complex diseases. While the majority of eQTL identified in genome-wide analyses impact a single gene, eQTL that impact many genes are particularly val...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448815/ https://www.ncbi.nlm.nih.gov/pubmed/28505156 http://dx.doi.org/10.1371/journal.pcbi.1005537 |