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An independent component analysis confounding factor correction framework for identifying broad impact expression quantitative trait loci

Genome-wide expression Quantitative Trait Loci (eQTL) studies in humans have provided numerous insights into the genetics of both gene expression and complex diseases. While the majority of eQTL identified in genome-wide analyses impact a single gene, eQTL that impact many genes are particularly val...

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Detalles Bibliográficos
Autores principales: Ju, Jin Hyun, Shenoy, Sushila A., Crystal, Ronald G., Mezey, Jason G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448815/
https://www.ncbi.nlm.nih.gov/pubmed/28505156
http://dx.doi.org/10.1371/journal.pcbi.1005537