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PknG senses amino acid availability to control metabolism and virulence of Mycobacterium tuberculosis

Sensing and response to changes in nutrient availability are essential for the lifestyle of environmental and pathogenic bacteria. Serine/threonine protein kinase G (PknG) is required for virulence of the human pathogen Mycobacterium tuberculosis, and its putative substrate GarA regulates the tricar...

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Detalles Bibliográficos
Autores principales: Rieck, Barbara, Degiacomi, Giulia, Zimmermann, Michael, Cascioferro, Alessandro, Boldrin, Francesca, Lazar-Adler, Natalie R., Bottrill, Andrew R., le Chevalier, Fabien, Frigui, Wafa, Bellinzoni, Marco, Lisa, María-Natalia, Alzari, Pedro M., Nguyen, Liem, Brosch, Roland, Sauer, Uwe, Manganelli, Riccardo, O’Hare, Helen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448819/
https://www.ncbi.nlm.nih.gov/pubmed/28545104
http://dx.doi.org/10.1371/journal.ppat.1006399