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Dietary constituent, decanoic acid suppresses the excitability of nociceptive trigeminal neuronal activity associated with hypoalgesia via muscarinic M(2) receptor signaling

BACKGROUND: Although decanoic acid (DA) is thought to act as a muscarinic cholinergic agonist, effect of DA on nociceptive behavioral responses and the excitability of nociceptive neuronal activity under in vivo conditions remain to be determined. The aim of the present study, therefore, was to inve...

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Detalles Bibliográficos
Autores principales: Noguchi, Yuna, Matsuzawa, Nichiwa, Akama, Youichi, Sekiguchi, Kenta, Takehana, Shiori, Shimazu, Yoshihito, Takeda, Mamoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448867/
https://www.ncbi.nlm.nih.gov/pubmed/28474958
http://dx.doi.org/10.1177/1744806917710779